Uryu Kamihate has had a rough start to life, but plans to forget it all by achieving his dream-matriculating into medical school. But when he arrives at his new foster home, a working shrine, his dream of a quiet place to study goes up in smoke. Not only will he be living with the three beautiful, lively Amagami sisters-but he learns that he must marry one of them and take over the shrine!
Spring break is over, and a new semester begins! But wait, Uryu’s new school is the same as Yuna's?! If they’re to survive, no one can know that they live together! There’s no end to the heart-stopping episodes as, on top of keeping his home life secret at school, Uryu also finds himself playing bodyguard to Yae and guardian to Asahi. As the sisters’ secrets are slowly revealed, what new mysteries must Uryu unravel?!