"The Orphanage" is a complex where monsters exist. The Raiders are tasked with capturing them whilst Arthur burns down the labs where they are being created. Eventually, he discovers the truth of what these monsters truly are alongside a group of ragtag cast of characters. This discovery is the catapult that starts a rebellious war against the societal structure being enforced.
Jesse has teamed up with the Rainbow Cubs to find information about his missing brother but this quickly escalates into a fight for their own survival.