In the year 20XX geneticist Hortense Taylor shocked the world when she created a super-soldier formula that would infuse humans with wolf-like senses, agility, and superhuman strength, however many of the male soldiers mutated into wolf-like creatures called Lycosapiens. With their overwhelming numbers, these creatures drove humanity underground, and only the enhanced soldiers of the Sister Hoods can set things right.
Welcome to a world where humanity have been driven into hiding. And the organization REALM has been tasked with the responsibility of protecting innocents and eventually defeating the Lycosapien menace. Savannah, a REALM officer, and a member of their army of super soldiers known as the Sister Hoods starts her nightly patrol.