The son of a famous pianist, music student Shinichi Chiaki dreams of studying abroad and becoming a conductor like his mentor. Unfortunately, his fear of flying grounds his lofty plans! As he watches other classmates achieve what he has always wanted, Shinichi wonders if he should quit music altogether. Then one day he meets fellow student Megumi Noda, also known as Nodame. This oddball girl cannot cook, clean, or even read a music score, but she can play the piano in incomparable Cantabile style. And she teaches Chiaki something that he has forgotten: to enjoy his music, no matter where he is.
All Chiaki ever wanted was to become a great conductor, and now it’s finally happening: He’s leading his own orchestra. He’s worked hard to get this far, but he still has so much to do. His musicians are sloppy, unmotivated, and out of practice. Chiaki’s ready to devote his life to making his dreams come true–but will they include Nodame, the girl who loves him?