In the distant future, two odd siblings find themselves in a crazy mess: Bimbo, an extremely air-headed nymphomaniac, and Hermit, a reclusive misanthrope, have unwittingly sold their souls to the Grim Reaper himself. Now, they’re stuck working for Grim’s morally dubious temp job business, "Grim’s Lil Helpers." With the help of their homicidal, talking pet rat, Scratchy, and backed by their enigmatic boss Grim, Bimbo and Hermit must navigate the bizarre chaos of Lycoris City and it's inhabits.
Bimbo, Hermit and Scratchy are pulled from their odd lives when Grim, their shadowy boss, assigns them an outrageous task: assassinate Lucifer for cheating on his wife.