Angelo Mortalli has become the ultimate killing machine. His memories were erased and his blood was infused with microscopic computers called nanites. These nanites allow him to heal wounds quickly, dominate electronic devices, and fully control every aspect of his body to maximize his physical capabilities. A modern-day Frankenstein, he wages a one man war-- taking out the mob, the police and his covert government creators-- in his struggle to find out who he was and what he has become.
Bloodshot tries getting in the Christmas spirit-- which is pretty hard to do when the entire New York mafia is gunning for you! Convinced that Bloodshot has broken their truce, the Carboni crime family launches another manhunt. But this time, they have something Bloodshot wants. Something worth killing for. Bloodshot's vicious rivalry with the New York mob starts anew!